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3-hydroxybutyrate dehydrogenase : ウィキペディア英語版 | 3-hydroxybutyrate dehydrogenase
In enzymology, a 3-hydroxybutyrate dehydrogenase () is an enzyme that catalyzes the chemical reaction :(''R'')-3-hydroxybutanoate + NAD+ acetoacetate + NADH + H+ Thus, the two substrates of this enzyme are (''R'')-3-hydroxybutanoate and NAD+, whereas its three products are acetoacetate, NADH, and H+. This enzyme belongs to the family of oxidoreductases, to be specific, those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (''R'')-3-hydroxybutanoate:NAD+ oxidoreductase. Other names in common use include NAD+-''beta''-hydroxybutyrate dehydrogenase, hydroxybutyrate oxidoreductase, ''beta''-hydroxybutyrate dehydrogenase, D-''beta''-hydroxybutyrate dehydrogenase, D-3-hydroxybutyrate dehydrogenase, D-(–)-3-hydroxybutyrate dehydrogenase, ''beta''-hydroxybutyric acid dehydrogenase, 3-D-hydroxybutyrate dehydrogenase, and ''beta''-hydroxybutyric dehydrogenase. This enzyme participates in synthesis and degradation of ketone bodies and butanoate metabolism. == Structural studies ==
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes and .
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